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货号： bsm-33172M-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bsm-33172M-Cy5.5
- 英文名称
- Anti-Lactoferrin/Cy5.5
- 中文名称
- Cy5.5标记的乳铁蛋白单克隆抗体
- 别 名
- CKRX; GIG12; Growth inhibiting protein 12; HLF2; Homo sapiens chemokine receptor X; Kaliocin 1; Lactoferrin; Lactoferroxin A; Lactoferroxin B; Lactoferroxin C; Lactoferroxin-C; Lactotransferrin; LF; LTF; Neutrophil lactoferrin; Talalactoferrin alfa; Talalactoferrin; TRFL_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 心血管 细胞生物 免疫学
- 抗体来源
- Mouse
- 克隆类型
- Monoclonal
- 克 隆 号
- 3A1
- 交叉反应
- Human,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 77kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Lactoferrin
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein G
- 储 存 液
- Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.
Function:
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.
Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration.
Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors.
The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.
Isoform DeltaLf: transcription factor with antiproliferative properties and inducing cell cycle arrest. Binds to DeltaLf response element found in the SKP1, BAX, DCPS, and SELH promoters.
Subunit:
Monomer. Found in a complex with LTF, CLU, EPPIN and SEMG1.
Subcellular Location:
Isoform 1: Secreted. Isoform DeltaLf: Cytoplasm. Nucleus.
Post-translational modifications:
Isoform DeltaLf: Ubiquitinated at Lys-379 and Lys-391.
Similarity:
Belongs to the transferrin family.
Contains 2 transferrin-like domains.
Database links:Entrez Gene: 4057 Human
Entrez Gene: 17002 Mouse
Entrez Gene: 301034 Rat
Omim: 150210 Human
SwissProt: P02788 Human
SwissProt: P08071 Mouse
Unigene: 529517 Human
Unigene: 282359 Mouse
Unigene: 218647 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.