产品中心
当前位置：首页>产品中心Anti-SLIRP/C14orf156/Cy5.5
货号： bs-21033R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-21033R-Cy5.5
- 英文名称
- Anti-SLIRP/C14orf156/Cy5.5
- 中文名称
- Cy5.5标记的14号染色体开放阅读框156抗体
- 别 名
- C14orf156; Chromosome 14 open reading frame 156; DC50;DC23; PD04872; SLIRP; SRA stem loop interacting RNA binding protein, mitochondrial.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 生长因子和激素 结合蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 12kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SLIRP/C14orf156
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Steroid receptor RNA activator (SRA, or SRA1; MIM 603819) is a complex RNA molecule containing multiple stable stem-loop structures that functions in coactivation of nuclear receptors. SLIRP interacts with stem-loop structure-7 of SRA (STR7) and modulates nuclear receptor transactivation (Hatchell et al., 2006 [PubMed 16762838]).[supplied by OMIM, Mar 2008]
Function:
RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation.
Subcellular Location:
Mitochondrial and Nuclear; Predominantly mitochondrial.
Tissue Specificity:
Ubiquitously expressed, with highest level in heart, liver, skeletal muscle and testis.
Similarity:
Contains 1 RRM (RNA recognition motif) domain.
Database links:Entrez Gene: 81892Human
Omim: 610211Human
SwissProt: Q9GZT3Human
Unigene: 655105Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.