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货号： bs-19699R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19699R-Cy5.5
- 英文名称
- Anti-QTRT1/Cy5.5
- 中文名称
- Cy5.5标记的鸟嘌呤插入酶QTRT1抗体
- 别 名
- FP3235; Guanine insertion enzyme; qtrt1; Queuine tRNA ribosyltransferase 1; Queuine tRNA ribosyltransferase; Queuine tRNA-ribosyltransferase; TGT; TGT, 43 KD subunit; TGT, catalytic subunit; TGT_HUMAN; TGUT; tRNA guanine transglycosylase; tRNA-guanine transglycosylase.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Guinea Pig,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 44kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human QTRT1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, Feb 2012]
Function:
Interacts with QTRTD1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
Subcellular Location:
Cytoplasm. Mitochondrion. Nucleus. Weakly associates with mitochondria, possibly via QTRTD1.
Similarity:
Belongs to the queuine tRNA-ribosyltransferase family.
Database links:Entrez Gene: 476711Dog
Entrez Gene: 81890Human
Entrez Gene: 60507Mouse
Entrez Gene: 64016Rat
Entrez Gene: 393985Zebrafish
Omim: 609615Human
SwissProt: Q9BXR0Human
SwissProt: Q9JMA2Mouse
SwissProt: Q4QR99Rat
SwissProt: Q7SYK1Zebrafish
Unigene: 631638Human
Unigene: 436579Mouse
Unigene: 53858Rat
Unigene: 9747Zebrafish
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.