产品中心
当前位置:首页>产品中心Anti-HBeAg (2E9)
货号: bsm-2022M 基本售价: 860.0 元 规格: 50ul
- 规格:50ul
- 价格:860.00元
- 规格:100ul
- 价格:1580.00元
产品信息
- 产品编号
- bsm-2022M
- 英文名称
- HBeAg (2E9)
- 中文名称
- 人乙型肝炎e抗原单克隆(包被)抗体
- 别 名
- Hepatitis B Virus E Antigen; HBe antigen; HBeAg; HBVgp4; Pre C,C; Precore protein; Precore/core; Precore/core ORF; Precore/core protei; HBEAG_HBVD3; External core antigen; HBeAg; p25.
- 规格价格
- 50ul/860元购买 100ul/1580元购买 大包装/询价
- 说 明 书
- 50ul 100ul
- 研究领域
- 免疫学 细菌及病毒
- 抗体来源
- Mouse
- 克隆类型
- Monoclonal
- 克 隆 号
- 2E9
- 交叉反应
- Hepatitis B virus
- 产品应用
- ELISA=1:500-1000 IHC-F=1:400-800 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 18kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- HBeAg full length protein:
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein G
- 储 存 液
- 0.01M TBS(pH7.4) with 0.03% Proclin300
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Hepatitis B e-antigen (HBeAg) is a viral protein associated with HBV infections. Unlike the surface antigen, the e-antigen is found in the blood only when there are viruses also present. When the virus goes into “hiding,” the e-antigen will no longer be present in the blood. HBeAg is often used as a marker of ability to spread the virus to other people (infectivity). Measurement of e-antigen may also be used to monitor the effectiveness of HBV treatment; successful treatment will usually eliminate HBeAg from the blood and lead to development of antibodies against e-antigen (anti-HBe). There are some types (strains) of HBV that do not make e-antigen; these are especially common in the Middle East and Asia. In areas where these strains of HBV are common, testing for HBeAg is not very useful.
Function:
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells. This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections.
Subunit:
Homodimerizes.
Subcellular Location:
Secreted. Host nucleus.
Post-translational modifications:
Phosphorylated.
Cleaved by host furin.
Similarity:
Belongs to the orthohepadnavirus precore antigen family.
SWISS:
Q89714
Gene ID:
944568
Database links:Entrez Gene: 944568 Hepatitis B virus
SwissProt: Q89714 Hepatitis B virus
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
大量商议
(bsm-2023M,bsm-2022M)可用于双抗夹心。