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货号： bsm-30062M-APC 基本售价： 440.0 元 规格： 25T
- 规格：25T
- 价格：440.00元
- 规格：100T
- 价格：1000.00元
产品信息
- 产品编号
- bsm-30062M-APC
- 英文名称
- human CD3-APC
- 中文名称
- APC标记小鼠抗人CD3单克隆抗体
- 别 名
- CD3 epsilon; CD3e; CD3e antigen epsilon polypeptide (TiT3 complex); CD3E antigen epsilon polypeptide; CD3E antigen, epsilon subunit; CD3e molecule epsilon; CD3e molecule, epsilon (CD3 TCR complex); CD3e molecule, epsilon (CD3-TCR complex); CD3E_HUMAN; IMD18; T cell antigen receptor complex epsilon subunit of T3; T cell surface antigen T3/Leu 4 epsilon chain; T cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE. APC anti-human CD3;
- 规格价格
- 25T/440元购买 100T/1000元购买 大包装/询价
- 说 明 书
- 25T 100T
- 研究领域
- 抗体来源
- Mouse
- 克隆类型
- Monoclonal
- 克 隆 号
- HIT3a
- 交叉反应
- Human,
- 产品应用
- Flow-Cyt=20μl/Test （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 20kDa
- 细胞定位
- 细胞膜
- 性 状
- Liquid
- 免 疫 原
- :
- 亚 型
- IgG2a
- 纯化方法
- affinity purified by Protein G
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].
Function:
The CD3 complex mediates signal transduction.
Subunit:
The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Similarity:
Contains 1 Ig-like (immunoglobulin-like) domain.
Contains 1 ITAM domain.
SWISS:
P07766
Gene ID:
916
Database links:Entrez Gene: 916 Human
Omim: 186830 Human
SwissProt: P07766 Human
Unigene: 3003 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Flow cytometry staining of normal human peripheral blood cells with CD3/APC (bsm-30062M-APC)(Red histogram) or Mouse IgG2a Isotype Control APC (C03-12004)(Blue histogram). Total cells were used for analysis.