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货号： bs-18662R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18662R-Cy5.5
- 英文名称
- Anti-MBIP/MAP3K12 binding inhibitory protein 1/Cy5.5
- 中文名称
- Cy5.5标记的MAP3K12结合抑制蛋白1抗体
- 别 名
- MAP3K12 binding inhibitory protein 1; MAP3K12-binding inhibitory protein 1; MAPK upstream kinase binding inhibitory protein; MAPK upstream kinase-binding inhibitory protein; MBIP; MBIP1_HUMAN; MUK binding inhibitory protein; MUK-binding inhibitory protein; OTTHUMP00000178844.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 39kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MBIP/MAP3K12 binding inhibitory protein 1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Subunit:
Component of the ADA2A-containing complex (ATAC), composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, CSRP2BP and WDR5.
Subcellular Location:
Nucleus. Cytoplasm. Shows a cytoplasmic localization when coexpressed with MAP3K12.
Tissue Specificity:
Ubiquitous. High expression seen in the heart and lung.
Database links:Entrez Gene: 51562Human
Entrez Gene: 217588Mouse
Entrez Gene: 362740Rat
Omim: 609431Human
SwissProt: Q9NS73Human
SwissProt: Q99LQ1Mouse
Unigene: 368647Human
Unigene: 25656Mouse
Unigene: 24202Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.