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货号： bs-14364R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-14364R-Cy5.5
- 英文名称
- Anti-GRP/Cy5.5
- 中文名称
- Cy5.5标记的促胃泌素释放肽抗体
- 别 名
- Gastrin releasing peptide; BN; Bombesin; GRP 10; GRP10; Neuromedin C; NeuromedinC; Pre progastrin releasing peptide; preproGRP; proGRP; GRP_HUMAN. Gastrin releasing peptide precursor.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 神经生物学 信号转导 生长因子和激素 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 3kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from mouse Gastrin Releasing Peptide
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Function:
GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent memory for fear.
Subcellular Location:
Secreted.
Tissue Specificity:
Highly expressed both in the lateral nucleus of the amygdala, and in regions sending synaptic projections to the lateral nucleus.
Similarity:
ngs to the bombesin/neuromedin-B/ranatensin family.
Database links:Entrez Gene: 2922Human
Entrez Gene: 225642Mouse
Entrez Gene: 171101Rat
Omim: 137260Human
SwissProt: P07492Human
SwissProt: Q8R1I2Mouse
SwissProt: P63153Pig
SwissProt: P24393Rat
Unigene: 153444Human
Unigene: 20298Mouse
Unigene: 10930Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.