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货号： bs-18297R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18297R-Cy5.5
- 英文名称
- Anti-LIPT2/Cy5.5
- 中文名称
- Cy5.5标记的硫辛酰连接酶2抗体
- 别 名
- EC 2.3.1.181; FCT2; Lipoate-protein ligase B; Lipoyl(octanoyl) transferase 2 (putative); Lipoyl/octanoyl transferase; Lipt2; LIPT2_HUMAN; mitochondrial; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase; OTTHUMP00000230589; OTTHUMP00000230590; OTTHUMP00000230591; Putative lipoyltransferase 2; Putative lipoyltransferase 2, mitochondrial; Putative octanoyltransferase, mitochondrial; SLC22A16.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导 新陈代谢 线粒体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 23kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LIPT2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
LIPT2 is a 231 amino acid mitochondrial protein that belongs to the LipB family. LIPT2 catalyzes the exchange of octanoic acid from octanoyl-acyl-carrier-protein to lipoate-dependent enzymes. The gene encoding LIPT2 maps to human chromosome 11, which comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.
Function:
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
Subcellular Location:
Mitochondrion.
Similarity:
Belongs to the lipB family.
Database links:Entrez Gene: 387787Human
Entrez Gene: 67164Mouse
Entrez Gene: 365314Rat
SwissProt: A6NK58 Human
SwissProt: Q9D009Mouse
Unigene: 591971Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.