产品中心
当前位置：首页>产品中心Anti-LD78 beta/CCL3L1/Cy5.5
货号： bs-18202R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18202R-Cy5.5
- 英文名称
- Anti-LD78 beta/CCL3L1/Cy5.5
- 中文名称
- Cy5.5标记的巨噬细胞炎性蛋白3样蛋白1抗体
- 别 名
- 464.2; C C motif chemokine 3 like 1; CCL3L1; CCL3L3; Chemokine (C C motif) ligand 3 like 1; Chemokine (C C motif) ligand 3 like 3; Chemokine (C C motif) ligand 3 like, centromeric; chemokine (CC motif) ligand 3 like 1; CL3L1_HUMAN; D17S1718; G0/G1 switch regulatory protein 19-2; G0S19-2; LD78; LD78 beta(1-70); LD78-beta(1-70); LD78-beta(5-70); LD78BETA; MGC104178; MGC12815; MGC182017; MIP1AP; PAT 464.2; SCYA3L; SCYA3L1; Small inducible cytokine A3 like 1 precursor; Small-inducible cytokine A3-like 1; Tonsillar lymphocyte LD78 beta; Tonsillar lymphocyte LD78 beta protein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Recombinant Fragment
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 8kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LD78 beta/CCL3L1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals, where most individuals have one to six copies, and a minority of individuals have zero or more than six copies. There are conflicting reports about copy number variation of this gene and its correlation to disease susceptibility.[provided by RefSeq, Apr 2014]
Function:
Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5.
Subcellular Location:
Secreted.
Post-translational modifications:
The N-terminal processed forms LD78-beta(3-70) and LD78-beta(5-70) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. The cleavage to yield LD78-beta(3-70) is probably achieved by DPP4.
Similarity:
Belongs to the intercrine beta (chemokine CC) family.
Database links:Entrez Gene: 414062Human
Entrez Gene: 6349Human
Omim: 601395Human
Omim: 609468Human
SwissProt: P16619Human
Unigene: 512304Human
Unigene: 512683Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.