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货号： bs-10940R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-10940R-Cy5.5
- 英文名称
- Anti-phospho-Ephrin B2 (Tyr311/316)/Cy5.5
- 中文名称
- Cy5.5标记的磷酸化Ephrin B2抗体
- 别 名
- phospho-Ephrin B2 (Tyr311+Tyr316); Ephrin B2 (phospho Y311 + Y316); CEK5 ligand; EFNB1; ELK L; EphrinB; Ephrin-B; ELK ligand; ELKL; EPH related receptor tyrosine kinase ligand 2; Ephrin B Precursor; Ephrin B1; Ephrin B2; LERK 2; LERK2; EFNB1_HUMAN; EFNB2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 36kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated Synthesised phosphopeptide derived from human Ephrin B2 around the phosphorylation site of Tyr311/316)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.
Subunit:
Interacts with GRIP1 and GRIP2. Binds to Nipah virus G protein.
Subcellular Location:
Membrane; single pass type I membrane protein.
Tissue Specificity:
Highly expressed in brain; expressed in embryonic floor plate, roof plate and hindbrain segments.
Similarity:
Belongs to the ephrin family.
Contains 1 ephrin RBD (ephrin receptor-binding) domain.
Database links:Entrez Gene: 1947Human
Entrez Gene: 1948Human
Entrez Gene: 13641Mouse
Entrez Gene: 13642Mouse
Entrez Gene: 25186Rat
Omim: 300035Human
Omim: 600527Human
SwissProt: P52799Human
SwissProt: P98172Human
SwissProt: P52795Mouse
SwissProt: P52800Mouse
SwissProt: P52796Rat
SwissProt: Q6P7B6Rat
Unigene: 144700Human
Unigene: 149239Human
Unigene: 44398Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.