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货号： bs-17896R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17896R-Cy5.5
- 英文名称
- Anti-MTUS2/Cy5.5
- 中文名称
- Cy5.5标记的微管相关肿瘤抑制蛋白2抗体
- 别 名
- +TIP of 150 kDa; 5730592G18Rik; A730013O20Rik; AU067634; C130038G02Rik; Cardiac zipper protein; CAZIP; Gm763; KIAA0774; Microtubule plus-end tracking protein TIP150; Microtubule-associated tumor suppressor candidate 2; mKIAA0774; Mtus2; MTUS2_HUMAN; OTTHUMP00000018187; OTTHUMP00000018188; RP11-274A8.2; TIP150; Tracking protein of 150 kDa.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 150kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MTUS2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Comprising nearly 4% of human DNA, chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. The KIAA0774 gene product has been provisionally designated KIAA0774 pending further characterization
Function:
Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip.
Subcellular Location:
Cytoplasm > cytoskeleton. Associated with the microtubule network at the growing distal tip (the plus-end) of microtubules.
Tissue Specificity:
Detected in embryonic stem cells differentiating to cardiomyocytes.
Similarity:
In the C-terminal section; belongs to the MTUS1 family.
Database links:Entrez Gene: 23281Human
Entrez Gene: 77521Mouse
SwissProt: Q5JR59Human
SwissProt: Q3UHD3Mouse
Unigene: 22287Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.