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货号： bs-17611R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17611R-Cy5.5
- 英文名称
- Anti-CCDC49/Cy5.5
- 中文名称
- Cy5.5标记的卷曲螺旋结构域蛋白49抗体
- 别 名
- Coiled-coil domain-containing protein 49; CWC25_HUMAN; Pre-mRNA-splicing factor CWC25 homolog.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 50kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CCDC49
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Spliceosomes are large ribonucleoproteins that remove introns from nuclear pre-mRNA in a two-step reaction. CCDC49 is a 425 amino acid protein that is involved in the catalytic steps of splicing in Saccharomyces cerevisiae. CCDC49 associates with a component of the Prp19-associated complex, CEF1, which is involved in spliceosome activation. It is likely that CCDC49 facilitates juxtaposition of the 5’ splice site and branch point during the final step in the first catalytic reaction. There are two isoforms of CCDC49 that are produced as a result of alternative splicing events.
Similarity:
Belongs to the CWC25 family.
Database links:Entrez Gene: 613278 Cow
Entrez Gene: 91050 Human
Entrez Gene: 100503884 Mouse
Entrez Gene: 688939 Rat
SwissProt: Q0VCP9 Cow
SwissProt: Q6ZUS6 Human
Unigene: 106432 Human
Unigene: 332379 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.