产品中心
当前位置：首页>产品中心Anti-Mannan Binding Lectin
货号： bs-23322R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-23322R
- 英文名称
- Mannan Binding Lectin
- 中文名称
- 甘露聚糖结合凝集素抗体
- 别 名
- Mbl2; L-MBP; MBL; MBL-C; MBP-C; COLEC 1; COLEC1; HSMBPC; Mannan binding protein; Mannose binding lectin (protein C) 2 soluble; Mannose binding lectin 2 soluble; Mannose binding lectin; Mannose binding lectin protein C2 soluble opsonic defect; Mannose binding protein; Mannose binding protein C; Mannose binding protein C precursor; MBL 2; MBP 1; MBP; MBP C; MBP1; MBPC; MGC116832; MGC116833; Opsonic defect; protein C ; Soluble mannose binding lectin; MBL2_HUMAN.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- WB=1:500-2000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 27kDa
- 细胞定位
- 分泌型蛋白
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Mannan Binding Lectin:151-248/248
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008].
Function:
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
Subunit:
Oligomeric complex of 3 or more homotrimers. Interacts with MASP1 and MASP2. Interacts with MEP1A and MEP1B and may inhibit their catalytic activity.
Subcellular Location:
Secreted.
Tissue Specificity:
Plasma protein produced mainly in the liver.
Similarity:
Contains 1 C-type lectin domain.
Contains 1 collagen-like domain.
SWISS:
P11226
Gene ID:
4153
Database links:Entrez Gene: 4153 Human
Entrez Gene: 17195 Mouse
Omim: 154545 Human
SwissProt: P11226 Human
SwissProt: P41317 Mouse
Unigene: 499674 Human
Unigene: 30045 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.