产品中心
当前位置：首页>产品中心Anti-SFXN1/Cy5.5
货号： bs-17306R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17306R-Cy5.5
- 英文名称
- Anti-SFXN1/Cy5.5
- 中文名称
- Cy5.5标记的三羧酸载体蛋白SFXN1抗体
- 别 名
- FLJ12876; SFXN1; SFXN1_HUMAN; Sideroflexin 1; Sideroflexin-1; TCC; Tricarboxylate carrier protein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 神经生物学 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 36kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SFXN1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The sideroflexin (SFXN) family is comprised of SFXN1, SFXN2, SFXN3, SFXN4 and SFXN5. SFXN1, also designated tricarboxylate carrier protein TCC, is the most highly characterized family member. The ubiquitously expressed SFXN1 protein resides as an integral protein of the mitochondrial inner membrane. It functions as an essential component of the shuttle system that transports mitochondrial acetyl-CoA into the cytosol, where lipogenesis occurs. The SFXN1 gene is mutated in flexed-tail (f/f) mice, which display axial skeletal abnormalities and a transient embryonic and neonatal anemia characterized by pathologic intramitochondiral iron deposits in erythrocytes. Therefore, SFXN1 is also thought to facilitate the transport of a component required for iron utilization into mitochondria. All SFXN family members show expression in pancreatic islet cells. SFXN5 displays a citrate transport activity and is primarily expressed in brain.
Function:
Might be involved in the transport of a component required for iron utilization into or out of the mitochondria.
Subcellular Location:
Mitochondrion membrane.
Similarity:
Belongs to the sideroflexin family.
Database links:Entrez Gene: 94081Human
Entrez Gene: 14057Mouse
Entrez Gene: 364678Rat
GenBank: NM_022754Human
SwissProt: Q9H9B4Human
SwissProt: Q99JR1Mouse
SwissProt: Q63965Rat
Unigene: 369440Human
Unigene: 134191Mouse
Unigene: 115752Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.