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货号： bs-17053R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17053R-Cy5.5
- 英文名称
- Anti-KIF26A/Cy5.5
- 中文名称
- Cy5.5标记的驱动蛋白家族成员26A抗体
- 别 名
- DKFZP434N178; FLJ22753; KI26A_HUMAN; KIAA1236; KIF 26A; KIF26A; KIF26A variant protein; Kinesin family member 26A; Kinesin like protein KIF26A; Kinesin-like protein KIF26A.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 195kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human KIF26A
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF26A (kinesin family member 26A) is a 1,882 amino acid protein that contains one N-terminal kinesin-motor domain and belongs to the kinesin-like protein family. The kinesin-motor domain is responsible for the ATP-dependent movement of KIF26A across microtubules.
Function:
Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity.
Subcellular Location:
Cytoplasm >cytoskeleton.
Similarity:
Belongs to the kinesin-like protein family. KIF26 subfamily.
Contains 1 kinesin-motor domain.
Database links:Entrez Gene: 26153Human
Omim: 613231Human
SwissProt: Q9ULI4Human
Unigene: 134970Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.