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货号： bs-17018R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17018R-Cy5.5
- 英文名称
- Anti-KIAA1618/Cy5.5
- 中文名称
- Cy5.5标记的KIAA1618蛋白抗体
- 别 名
- ALK lymphoma oligomerization partner on chromosome 17; ALO17; RN213_HUMAN; Hypothetical protein LOC57714; Protein ALO17.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 591kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human KIAA1618
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
There are three isoforms. A chromosomal aberration involving KIAA1618 is associated with anaplastic large-cell lymphoma (ALCL). Translocation t(2;17)(p23;q25) with ALK.
Function:
Probable E3 ubiquitin-protein ligase that may play a role in angiogenesis. May also have an ATPase activity.
Subcellular Location:
Cytoplasm
Tissue Specificity:
Widely expressed (at protein level).
Post-translational modifications:
Autoubiquitinates.
DISEASE:
Moyamoya disease 2 (MYMY2) [MIM:607151]: A progressive cerebral angiopathy characterized by bilateral intracranial carotid artery stenosis and telangiectatic vessels in the region of the basal ganglia. The abnormal vessels resemble a puff of smoke (moyamoya) on cerebral angiogram. Affected individuals can develop transient ischemic attacks and/or cerebral infarction, and rupture of the collateral vessels can cause intracranial hemorrhage. Hemiplegia of sudden onset and epileptic seizures constitute the prevailing presentation in childhood, while subarachnoid bleeding occurs more frequently in adults. {ECO:0000269|PubMed:21048783, ECO:0000269|PubMed:21799892}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
Similarity:
Contains 1 RING-type zinc finger.
Database links:Entrez Gene: 57714Human
SwissProt: Q9HCF4Human
Unigene: 514554Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.