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货号： bs-14413R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-14413R-Cy5.5
- 英文名称
- Anti-DPCD/Cy5.5
- 中文名称
- Cy5.5标记的原发性纤毛运动障碍相关蛋白DPCD抗体
- 别 名
- Deleted in a mouse model of primary ciliary dyskinesia; DKFZp566F084; dpcd; DPCD protein; DPCD_HUMAN; OTTHUMP00000020329; Protein DPCD; RP11 529I10.4; RP11-529I10.4.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管 细胞生物 细胞分化
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 23kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DPCD
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
DPCD is a 203 amino acid protein that is expressed at higher levels during ciliated cell differentiation, suggesting that DPCD plays a role in the function or formation of ciliated cells. In primary ciliary dyskinesia (PCD), an autosomal recessive disease that is caused by mutations affecting the proper function of cilia, an exon in the DPCD gene is deleted. The phenotype of PCD is variable, though it may include symptoms such as sinus inverse totalis, infertility or otitis media. In severe cases, patients develop end-stage bronchiectasis and require a lung transplantation. DPCD is highly expressed in testis, with weak expression in heart, pancreas and skeletal muscle.
Function:
May play a role in the formation or function of ciliated cells.
Tissue Specificity:
Highly expressed in the testis. Weakly expressed in pancreas, skeletal muscle and heart. Expression increases during ciliated cell differentiation.
Similarity:
Belongs to the DPCD family.
Database links:Entrez Gene: 25911Human
Entrez Gene: 516908Cow
Entrez Gene: 477800Dog
Entrez Gene: 226162Mouse
Entrez Gene: 294004Rat
SwissProt: Q24K21Cow
SwissProt: Q9BVM2Human
SwissProt: Q8BPA8Mouse
SwissProt: Q6AYM4Rat
Unigene: 658128Human
Unigene: 21978Mouse
Unigene: 50057Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.