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货号： bs-14233R-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-14233R-Cy5.5
- 英文名称
- Anti-DDX52/Cy5.5
- 中文名称
- Cy5.5标记的ATP依赖RNA解旋酶DDX52抗体
- 别 名
- ATP dependent RNA helicase ROK1 like; ATP-dependent RNA helicase ROK1-like; DDX52; DDX52_HUMAN; DEAD (Asp-Glu-Ala-Asp) box polypeptide 52; DEAD box protein 52; Probable ATP dependent RNA helicase DDX52; Probable ATP-dependent RNA helicase DDX52; ROK1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 发育生物学 转录调节因子 细胞分化 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 67kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DDX52
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DEAD box protein 52 (DDX52) is a 599 amino acid protein belonging to the DEAD box helicase family. Localized to the nucleus, DDX52 is phosphorylated by ATM or ATR upon DNA damage. DDX52 contains one helicase ATP-binding domain and one helicase C-terminal domain
Subcellular Location:
Nucleus >nucleolus.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.
Database links:Entrez Gene: 11056Human
Entrez Gene: 78394Mouse
Entrez Gene: 85432Rat
SwissProt: A5D7C1Cow
SwissProt: Q9Y2R4Human
SwissProt: Q8K301Mouse
SwissProt: Q99PT0Rat
Unigene: 51117Cow
Unigene: 590937Human
Unigene: 280544Mouse
Unigene: 18605Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.