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货号： bs-2815R 基本售价： 1580.0 元 规格： 100ul
产品信息
- 产品编号
- bs-2815R
- 英文名称
- phospho-CDC37 (Ser13)
- 中文名称
- 磷酸化细胞分化周期蛋白37抗体
- 别 名
- Cdc37 (phospho S13); p-Cdc37 (phospho S13); CDC 37; Cdc37; CDC37 cell division cycle 37 homolog; CDC37 cell division cycle 37 S cerevisiae homolog; CDC37 cell division cycle 37, S cerevisiae, homolog of; Cdc37 homolog; CDC37 protein; CDC37_HUMAN; CDC37A; cell division cycle 37; Cell division cycle 37 homolog; Hsp90 chaperone protein kinase targeting subunit; Hsp90 chaperone protein kinase targeting subunit p50Cdc37; Hsp90 chaperone protein kinase-targeting subunit; Hsp90 co chaperone Cdc37; Hsp90 co-chaperone Cdc37; p50; p50Cdc37; S cerevisiae hypothetical protein CDC37.
- 规格价格
- 100ul/1580元购买 大包装/询价
- 说 明 书
- 100ul
- 产品类型
- 磷酸化抗体
- 研究领域
- 细胞生物 细胞周期蛋白 激酶和磷酸酶 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep,
- 产品应用
- WB=1:500-2000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 44kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthesised phosphopeptide derived from human CDC37 around the phosphorylation site of Ser13:EV(p-S)DD
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene. The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK, as well as eIF-2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.
Function:
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
Subcellular Location:
Cytoplasm.
Post-translational modifications:
Constitutively sumoylated by UBE2I.
Similarity:
Belongs to the CDC37 family.
SWISS:
Q16543
Gene ID:
11140
Database links:Entrez Gene: 11140Human
Entrez Gene: 12539Mouse
Entrez Gene: 114562Rat
Omim: 605065Human
SwissProt: Q16543Human
SwissProt: Q61081Mouse
SwissProt: Q63692Rat
Unigene: 160958Human
Unigene: 32331Mouse
Unigene: 17982Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.