货号 | BAM3521 |
描述 | For ELISA the Antibody Pairs information:Capture antibody:MAB352;Detection antibody:BAM3521; and protein: 352-MS-010 |
别名 | D3F15S2; EC 3.4.21; hepatocyte growth factor-like protein homolog; HGFL; HGFLhepatocyte growth factor-like protein; macrophage stimulating 1 (hepatocyte growth factor-like); Macrophage stimulatory protein; Macrophage-stimulating protein; MSPDNF15S2; MST1; NF15S2; SF2 | 全称 | Macrophage Stimulating Protein/Macrophage Stimulating 1 [Hepatocyte Growth Factor-like] |
反应种属 | Human |
应用 | Western Blot(1 µg/mL) ELISA Capture (Matched Antibody Pair)(2-8 µg/mL ) ELISA Detection (Matched Antibody Pair)(0.5-2.0 µg/mL ) ELISA Standard ( ) |
目标/特异性 | Detects recombinant human (rh)MSP in direct ELISAs and Western blots. When used in combination with the monoclonal capture antibody (Catalog # MAB352) in sandwich ELISAs, less than 0.001% cross-reactivity was observed with rhHGF, rhIL-9 R, rhMSP alpha or rmMSP R. |
使用方法 | Western Blot: 1 µg/mL ELISA Capture (Matched Antibody Pair): 2-8 µg/mL ELISA Detection (Matched Antibody Pair): 0.5-2.0 µg/mL ELISA Standard : |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 4485 (Human); 15235 (Mouse); 24566 (Rat) |
纯化方式 | Protein A or G purified from ascites |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human MSP beta chain Accession # P26927 |
生物活性 | Human |
标记 | Biotin |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | MSP, also known as hepatocyte growth factor-like protein (HGFl), and scatter factor-2 (SF2), is a member of the HGF family of growth factors. It is secreted as a single chain inactive precursor which is proteolytically activated to yield a biologically active disulfide-linked heterodimer of the alpha and beta chains. MSP induces keratinocyte proliferation, bone resorption, and cell migration and shape change in resident macrophages. Heterodimeric MSP binds to and activates the cell surface receptor tyrosine kinase, RON/STK, which is expressed on mature macrophages, keratinocytes, and vascular endothelium of wounded skin. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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