| 货号 | MAB352-RD |
| 别名 | D3F15S2; EC 3.4.21; hepatocyte growth factor-like protein homolog; HGFL; HGFLhepatocyte growth factor-like protein; macrophage stimulating 1 (hepatocyte growth factor-like); Macrophage stimulatory protein; Macrophage-stimulating protein; MSP; MSPDNF15S2; MST1; NF15S2; SF2 | 全称 | Macrophage Stimulating Protein/Macrophage Stimulating 1 [Hepatocyte Growth Factor-like] |
| 反应种属 | Human |
| 应用 | Western Blot(1 礸/mL)<br/>ELISA Capture (Matched Antibody Pair)(2-8 礸/mL )<br/>ELISA Detection ( |
| 目标/特异性 | Detects human MSP alpha Chain in ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) HGF or rhIL‑6 is observed. |
| 使用方法 | Western Blot: 1 µg/mL Immunoaffinity Purification: Immobilized anti-MSP alpha chain antibody can be used to bind pro-MSP, mature MSP, and free alpha chain. ELISA Capture (Matched Antibody Pair): 2-8 µg/mL ELISA Detection (Matched Antibody Pair): 0.5-2.0 µg/mL ELISA Standard : |
| 来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 4485 (Human); 15235 (Mouse); 24566 (Rat) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. HIV?1 downregulates the expression and phosphorylation of receptor tyrosine kinase by targeting the NF??B pathway | |
| 纯化方式 | Immobilized anti-MSP alpha chain antibody can be used to bind pro-MSP, mature MSP, and free alpha chain. |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human MSP Met1-Gly711 Accession # AAA59872 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | MSP, also known as hepatocyte growth factor-like protein (HGFl), andscatter factor-2 (SF2), is a member of the HGF family of growthfactors. It is secreted as a single chain inactive precursor which isproteolytically activated to yield a biologically activedisulfide-linked heterodimer of the alpha and beta chains. MSP induceskeratinocyte proliferation, bone resorption, and cell migration andshape change in resident macrophages. Heterodimeric MSP binds to andactivates the cell surface receptor tyrosine kinase, RON/STK, which isexpressed on mature macrophages, keratinocytes, and vascularendothelium of wounded skin. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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