| 货号 | MAB4871 |
| 描述 | For ELISA the Antibody Pairs information：Capture antibody：MAB4871；Detection antibody：BAM4872; and protein: 487-C-010 |
| 别名 | C10; MRP-1; SCYA6 |
| 反应种属 | Mouse |
| 应用 | ELISA Capture (Matched Antibody Pair)(2-8 µg/mL ) ELISA Detection (Matched Antibody Pair)(0.5-2 µg/mL ) ELISA Standard ( ) |
| 目标/特异性 | Detects mouse CCL6/C10 in ELISAs. In sandwich immunoassays, no cross-reactivity or interference with recombinant mouse (rm) CCL3, rmCCL4, or rmCCL9/10 is observed. |
| 使用方法 | ELISA Capture (Matched Antibody Pair): 2-8 µg/mL ELISA Detection (Matched Antibody Pair): 0.5-2 µg/mL ELISA Standard : |
| 来源 | Sterile PBS to a final concentration of 0.5 mg/mL. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 20305 (Mouse); 287910 (Rat) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | E. coli-derived recombinant mouse CCL6/C10 Gly22-Ala116 Accession # P27784 |
| 生物活性 | Mouse |
| 标记 | Unconjugated |
| 溶解方法 | Sterile PBS to a final concentration of 0.5 mg/mL. |
| 背景 | Mouse CCL6, a member of the beta subfamily of chemokines, was initially identified as a transcript that is induced in bone marrow cells upon stimulation with GM-CSF. A human homologue for mouse CCL6 has not been identified. The mCCL6 cDNA encodes a 116 amino acid precursor protein with a hydrophobic signal peptide that is cleaved to yield a 95 amino acid mature protein. Compared to other chemokines, mCCL6 has a large N-terminal extension. The expression of CCL6 mRNA has been detected in mouse monocytes and neutrophils, where it is strongly induced upon GM-CSF stimulation. CCL6 expression has also been detected in an IL-2-dependent T cell line, where the expression is inhibited following T cell stimulation. Mouse CCL6 expression was also shown to be strongly induced by IL-4 in mouse macrophages. The gene for CCL6 has been mapped to mouse chromosome 11. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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