Recombinant PRMT7 protein
货号：
31395 基本售价：
6162.5 元 规格：
20 ug
产品信息
概述| 货号 | 31395 |
| 使用方法 | Recombinant PRMT7 is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.Specific Activity: Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3). Specifically mediates the symmetric dimethylation of histone H4 Arg-3 to form H4R3me2s. |
性能| 供应商 | Active Motif |
| 背景 | PRMT7 (Protein Arginine Methyltransferase 7) is a type I arginine methyltransferase. Arginine methylation is a common post-translational modification of histones and other cellular proteins. PRMT7 specifically mediates the symmetrical dimethylation of histone H4 at Arg3 to form H4R3me2s. PRMT7 plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruitment of DNA methyltransferases at these sites. PRMT7 may also play a role in embryonic stem cell (ESC) pluripotency. PRMT7 is also able to mediate arginine methylation of histone H2A and myelin basic protein (MBP) in vitro. However, the biological relevance of such results is unclear. |
| 运输条件 | Dry Ice |
| 存放说明 | Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 外观 | Full length recombinant PRMT7 protein expressed in Sf9 cells at a concentration of 0.8 mg/ml in 25 mM Tris pH 8.0, 300 mM NaCl, 5% Glycerol, 0.04% Triton X-100 and 0.2 mg/ml 3× Flag peptide. |
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参考图片Recombinant PRMT7 protein gel.
PRMT7 protein was run on a 10% SDS-PAGE gel and stained with Coomassie blue. |
