Recombinant BRD9 (130-259) protein
货号：
31382 基本售价：
5872.5 元 规格：
100 ug
产品信息
概述| 货号 | 31382 |
| 别名 | PRO9856; LAVS3040 |
| 使用方法 | Recombinant BRD9 (130-259) is suitable for use in binding assays, inhibitor screening, and selectivity profiling. |
性能| 供应商 | Active Motif |
| 背景 | Bromodomain-containing protein 9 (BRD9) belongs to the BET subclass of proteins, which are characterized by two N-terminal bromodomains and one ET (Extra Terminal) domain. BRDs associate with chromatin through their bromodomains that recognize acetylated histone lysine residues. Bromodomains function as ‘readers’ of these epigenetic histone marks and regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. The ET domain functions as a protein binding motif and exerts atypical serine-kinase activity. The BET family consists of at least four members in mouse and human, BRD2 (also referred to as FSRG1, RING3), BRD3 (FSRG2, ORFX), BRD4 (FSRG4, MCAP/HUNK1), and BRDT (FSRG3, BRD6) that function in the regulation of transcriptional activation and chromatin remodeling. There are five isoforms of BRD9 that are produced by alternative splicing. |
| 运输条件 | Dry Ice |
| 存放说明 | Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 外观 | Recombinant BRD9 (130-259) protein was expressed in E. coli cells and is supplied in 25 mM Tris-HCl pH 8.0, 500 mM NaCl, 0.04% Triton X-100, 20% glycerol, 1mM TCEP. Please refer to product insert upon arrival for lot-specific concentration. |
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