Recombinant UHRF1 protein
货号:
81015 基本售价:
5872.5 元 规格:
50 ug
产品信息
概述货号 | 81015 |
使用方法 | This protein is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
性能供应商 | Active Motif |
背景 | UHRF1 (Ubiquitin Like With PHD And Ring Finger Domains 1, also known as Np95, hNP95, ICBP90, RNF106, TDRD22, hUHRF1, huNp95) is a member of a subfamily of RING-finger type E3 ubiquitin ligases. UHRF1 binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. UHTR1 plays a major role in the G1/S transition by regulating topoisomerase IIΑ and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. UHRF1 is overexpressed in various cancers. UHRF1 plays a critical role in maintaining DNA methylation in mammalian cells. |
运输条件 | Dry Ice |
存放说明 | Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
外观 | Recombinant UHRF1 protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 5% glycerol. Please refer to product insert upon arrival for lot-specific concentration. |
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