Recombinant Mononucleosomes H3K4me1/H3K27ac - biotin
货号：
81003 基本售价：
5872.5 元 规格：
10 ug
产品信息
概述| 货号 | 81003 |
| 使用方法 | Recombinant Mononucleosomes H3K4me1/K27ac - biotinylated are suitable for use as substrate of enzymatic assay or other biochemical assay. |
性能| 供应商 | Active Motif |
| 背景 | In vivo, histones are wrapped around by DNA in chromatin. Therefore, nucleosomes are more physiologically relevant substrates than histones and histone-derived peptides for in vitro studies. More importantly, some histone methyltransferases are significantly more active, as well as specific, when using nucleosomal substrates in HMT assays, such as DOT1L and NSD family enzymes. Nucleosomes are also widely used in histone methyltransferase screening assays to identify small molecular inhibitors for drug discovery. |
| 运输条件 | Dry Ice |
| 存放说明 | Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 外观 | Recombinant Mononucleosomes H3K4me1/K27ac - biotinylated (10 µg protein + 10 µg DNA) are supplied in 10 mM Tris-HCl, pH 8.0, 1 mM EDTA, 2 mM DTT and 20% glycerol. Please refer to product insert upon arrival for lot-specific concentration. |
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