Recombinant Smyd2 protein
货号：
31323 基本售价：
5727.5 元 规格：
10 ug
产品信息
概述| 货号 | 31323 |
| 别名 | KMT3C; HSKM-B; ZMYND14 |
| 使用方法 | Recombinant Smyd2 is suitable for use in methyltransferase assays. A recommended starting point for the methyltransferase assay is 50-200 ng of recombinant protein per reaction. The molecular weight of the protein is ~52 kDa. |
性能| 供应商 | Active Motif |
| 背景 | Smyd2(SETandMYNDdomain containing protein 2) is a lysine methyltransferase that methylates both histones and non-histone proteins. Specifically, Smyd2 methylates histone H3 Lys4 (H3K4me1) and dimethylates histone H3 Lys36 (H3K36me2). Smyd2 also exhibits methyltransferase activity toward non-histone proteins such as p53 and pRb. Smyd2 monomethylates Lys370 of p53, leading to decreased DNA-binding activity and subsequent inhibition of p53-mediated transcriptional regulation. Smyd2 also monomethylates Lys860 of pRb. |
| 运输条件 | Dry Ice |
| 外观 | 10 µg recombinant Smyd2 protein supplied at a concentration of 2 µg/µl in 20 mM Tris-HCl, pH 7.3, 100 mM KCl, 0.2 mM EDTA and 20% glycerol. |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
