Cathepsin H Inhibitor Screening Kit (Fluorometric)
货号：
K164-100 基本售价：
7762.5 元 规格：
100assays
产品信息
概述| 货号 | K164-100 |
| 描述 | Cathepsin H (CTSH, EC 3.4.22.16), a lysosomal cysteine protease, is important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. BioVision’s Cathepsin H Inhibitor Screening Kit utilizes the ability of an active Cathepsin H to cleave a synthetic AFC-based peptide substrate to release free AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin H-specific inhibitor, the cleavage of this substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This simple and high-throughput adaptable assay kit can be used to screen/study/characterize potential inhibitors of Cathepsin H. |
| 同种亚型 | Rabbit IgG |
| 来源宿主 | Rabbit |
性能| 供应商 | Biovision |
| 检测类型 | Fluorescence (Ex/Em = 400/505 nm)• Applications - Screen/study/characterize potential inhibitors of Cathepsin H |
| 产品特色 | • Convenient & Rapid• High-throughput adaptable assay to screen/study/characterize the potential inhibitors of Cathepsin H• Cathepsin H inhibitor is included in the kit |
| 试剂盒组分 | • CTSH Assay Buffer• CTSH Reagent• Human Cathepsin H• CTSH Substrate• CTSH Inhibitor (1 mM) |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
