| 货号 | K147-100 |
| 描述 | Cathepsin B (CTSB, EC 3.4.22.1) is a lysosomal cysteine proteinase that is suggested to participate in intracellular degradation and turnover of proteins. It has also been implicated in tumor invasion and metastasis. Biovision’s Cathepsin B Inhibitor Screening Kit utilizes the ability of Cathepsin B to cleave the synthetic AFC based peptide substrate to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin B-specific inhibitor, the cleavage of the substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This simple and high-throughput adaptable assay kit can be used to screen/study/characterize the potential inhibitors of Cathepsin B. |
| 同种亚型 | Rabbit IgG |
| 来源宿主 | Rabbit |
| 供应商 | Biovision |
| 试剂盒组分 | • CTSB Reaction Buffer • CTSB Reagent • Cathepsin B (human) • CTSB Substrate, Ac-RR-AFC (10 mM) • CTSB Inhibitor (F-F-FMK, 1 mM) |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |