| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Efficiency of newly formulated camptothecin with ?-cyclodextrin-EDTA-Fe3O4 nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug
Authors: P Krishnan, M Rajan, S Kumari, S Sakinah, SP Priya, F Amira, L Danjuma, M Pooi Ling, S Fakurazi, P Arulselvan, A Higuchi, R Arumugam, AA Alarfaj, MA Munusamy, RA Hamat, G Benelli, K Murugan, SS Kumar
Sci Rep, 2017;7(1):10962. 2017
Long non-coding RNA MALAT1 contributes to cell apoptosis by sponging miR-124 in Parkinson disease
Authors: W Liu, Q Zhang, J Zhang, W Pan, J Zhao, Y Xu
Cell Biosci, 2017;7(0):19. 2017
Endogenous Two-Photon Excited Fluorescence Imaging Characterizes Neuron and Astrocyte Metabolic Responses to Manganese Toxicity
Authors: E Stuntz, Y Gong, D Sood, V Liaudanska, D Pouli, KP Quinn, C Alonzo, Z Liu, DL Kaplan, I Georgakoud
Sci Rep, 2017;7(1):1041. 2017
Elucidation of Molecular Mechanisms of Streptozotocin-Induced Oxidative Stress, Apoptosis, and Mitochondrial Dysfunction in Rin-5F Pancreatic ?-Cells
Authors: AMTA Nahdi, A John, H Raza
Oxid Med Cell Longev, 2017;2017(0):7054272. 2017
Cudraflavone C Induces Apoptosis of A375.S2 Melanoma Cells through Mitochondrial ROS Production and MAPK Activation
Authors: CW Lee, FL Yen, HH Ko, SY Li, YC Chiang, MH Lee, MH Tsai, LF Hsu
Int J Mol Sci, 2017;18(7):. 2017
Euphorbia factor L2 induces apoptosis in A549 cells through the mitochondrial pathway
Authors: M Lin, S Tang, C Zhang, H Chen, W Huang, Y Liu, J Zhang
Acta Pharm Sin B, 2017;7(1):59-64. 2017
Pterostilbene exerts anticancer activity on non-small-cell lung cancer via activating endoplasmic reticulum stress
Authors: Z Ma, Y Yang, S Di, X Feng, D Liu, S Jiang, W Hu, Z Qin, Y Li, J Lv, C Fan, X Yan, X Li
Sci Rep, 2017;7(1):8091. 2017
Inhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells
Authors: KY Kim, KI Park, SH Kim, SN Yu, SG Park, YW Kim, YK Seo, JY Ma, SC Ahn
Int J Mol Sci, 2017;18(5):. 2017
Bufalin sensitizes human bladder carcinoma cells to TRAIL-mediated apoptosis
Authors: KH Kang, MH Han, JW Jeong, C Park, SH Lee, HW Lee, SH Hong, YH Choi, SH Hong
Oncol Lett, 2017;14(1):853-859. 2017
Disrupting the blood-brain barrier by focused ultrasound induces sterile inflammation
Proc. Natl. Acad. Sci. U.S.A, 2016;0(0):. 2016
Pulchrin A, a New Natural Coumarin Derivative of Enicosanthellum pulchrum, Induces Apoptosis in Ovarian Cancer Cells via Intrinsic Pathway
PLoS ONE, 2016;11(5):e0154023. 2016
Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics
Elife, 2016;5(0):. 2016
Hydrogen Peroxide-Responsive Nanoparticle Reduces Myocardial Ischemia/Reperfusion Injury
J Am Heart Assoc, 2016;5(11):. 2016
The mitochondrial ubiquitin ligase plays an anti-apoptotic role in cardiomyocytes by regulating mitochondrial fission
J Cell Mol Med, 2016;0(0):. 2016
Anti-Cancer Effect of Lambertianic Acid by Inhibiting the AR in LNCaP Cells
Int J Mol Sci, 2016;17(7):. 2016
Upregulation of retinoic acid receptor-? reverses drug resistance in cholangiocarcinoma cells by enhancing susceptibility to apoptosis
Mol Med Rep, 2016;14(4):3602-8. 2016
Bacteroides fragilis Enterotoxin Upregulates Heme Oxygenase-1 in Intestinal Epithelial Cells via a Mitogen-Activated Protein Kinases- and NF-?B-Dependent Pathway, Leading to Modulation of Apoptosis
Authors: Su Hyuk Ko
Infect Immun, 2016;0(0):. 2016
Diosmin protects against ethanol-induced gastric injury in rats: novel anti-ulcer actions.
Authors: Arab H, Salama S, Omar H, Arafa E, Maghrabi I
PLoS ONE, 2015;10(3):e0122417. 2015
Augmented efficacy with the combination of blockade of the Notch-1 pathway, bortezomib and romidepsin in a murine MT-1 adult T-cell leukemia model.
Authors: Yu P, Petrus M, Ju W, Zhang M, Conlon K, Nakagawa M, Maeda M, Bamford R, Waldmann T
Leukemia, 2015;29(3):556-66. 2015
Curcumin-loaded nanoparticles enhance apoptotic cell death of U2OS human osteosarcoma cells through the Akt-Bad signaling pathway.
Authors: Peng S, Lee C, Hour M, Tsai S, Kuo D, Chen F, Shieh P, Yang J
Int J Oncol, 2014;44(1):238-46. 2014
Telmisartan attenuates colon inflammation, oxidative perturbations and apoptosis in a rat model of experimental inflammatory bowel disease.
Authors: Arab H, Al-Shorbagy M, Abdallah D, Nassar N
PLoS ONE, 2014;9(5):e97193. 2014
Upregulation of miR-18a-5p contributes to epidermal necrolysis in severe drug eruptions.
Authors: Ichihara A, Wang Z, Jinnin M, Izuno Y, Shimozono N, Yamane K, Fujisawa A, Moriya C, Fukushima S, Inoue Y, Ihn H
J Allergy Clin Immunol, 2014;133(4):1065-74. 2014
Enhancement of TWIK-related acid-sensitive potassium channel 3 (TASK3) two-pore domain potassium channel activity by tumor necrosis factor alpha.
Authors: El Hachmane M, Rees K, Veale E, Sumbayev V, Mathie A
J Biol Chem, 2014;289(3):1388-401. 2014
Protective effect of Aframomum melegueta phenolics against CCl(4)-induced rat hepatocytes damage; role of apoptosis and pro-inflammatory cytokines inhibition.
Authors: El-Halawany A, El Dine R, El Sayed N, Hattori M
Sci Rep, 2014;4(0):5880. 2014
Malignant melanoma cells acquire resistance to DNA interstrand cross-linking chemotherapeutics by p53-triggered upregulation of DDB2/XPC-mediated DNA repair.
Authors: Barckhausen C, Roos W, Naumann S, Kaina B
Oncogene, 2014;33(15):1964-74. 2014
Adverse signaling of scavenger receptor class B1 and PGC1s in alcoholic hepatosteatosis and steatohepatitis and protection by betaine in rat.
Authors: Varatharajalu R, Garige M, Leckey L, Arellanes-Robledo J, Reyes-Gordillo K, Shah R, Lakshman M
Am J Pathol, 2014;184(7):2035-44. 2014
Suberoylanilide hydroxamic acid-induced HeLa cell death is closely correlated with oxidative stress and thioredoxin 1 levels.
Authors: You B, Park W
Int J Oncol, 2014;44(5):1745-55. 2014
Erythropoietin protects cardiomyocytes from cell death during hypoxia/reperfusion injury through activation of survival signaling pathways.
Authors: Parvin A, Pranap R, Shalini U, Devendran A, Baker J, Dhanasekaran A
PLoS ONE, 2014;9(9):e107453. 2014
Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase.
Authors: Weizman, N, Krelin, Y, Shabtay-Orbach, A, Amit, M, Binenbaum, Y, Wong, R J, Gil, Z
Oncogene, 2014;33(29):3812-9. 2014
Soy soluble polysaccharide induces apoptosis in HCT116 human colon cancer cells via reactive oxygen species generation.
Authors: Ko Y, Jeong J, Choi Y, Ryu C
Mol Med Rep, 2013;8(6):1767-72. 2013
The ameliorative effects of L-2-oxothiazolidine-4-carboxylate on acetaminophen-induced hepatotoxicity in mice.
Authors: Choi, Jiwon, Park, Kwang-Hy, Kim, Sung Zoo, Shin, Jun Ho, Jang, Seon-Il
Molecules, 2013;18(3):3467-78. 2013
The novel carboxamide analog ITR-284 induces caspase-dependent apoptotic cell death in human hepatocellular and colorectal cancer cells.
Authors: Liao Y, Lu C, Lai K, Yang J, Kuo S, Wen Y, Fushiya S, Wu T
Mol Med Rep, 2013;7(5):1539-44. 2013
Combination of albendazole and 2-methoxyestradiol significantly improves the survival of HCT-116 tumor-bearing nude mice.
Authors: Ehteda, Anahid, Galettis, Peter, Pillai, Krishna, Morris, David L
BMC Cancer, 2013;13(0):86. 2013
Valproic acid inhibits the growth of HeLa cervical cancer cells via caspase-dependent apoptosis.
Authors: Han B, You B, Park W
Oncol Rep, 2013;30(6):2999-3005. 2013
Suppression of neuroinflammatory and apoptotic signaling cascade by curcumin alone and in combination with piperine in rat model of olfactory bulbectomy induced depression.
Authors: Rinwa P, Kumar A, Garg S
PLoS ONE, 2013;8(4):e61052. 2013
The critical role of mast cell-derived hypoxia-inducible factor-1alpha in human and mice melanoma growth.
Authors: Jeong H, Oh H, Nam S, Han N, Kim Y, Kim J, Lee S, Kim M, Moon P, Kim H, Oh H
Int J Cancer, 2013;132(11):2492-501. 2013
Implications of altered glutathione metabolism in aspirin-induced oxidative stress and mitochondrial dysfunction in HepG2 cells.
Authors: Raza H, John A,
PLoS ONE, 2012;7(4):e36325. 2012
Citrus aurantium L. exhibits apoptotic effects on U937 human leukemia cells partly through inhibition of Akt.
Authors: Han MH, Lee WS, Lu JN
Int. J. Oncol., 2012;40(6):2090-6. 2012
Proteasome inhibitors prevent caspase-1-mediated disease in rodents challenged with anthrax lethal toxin.
Authors: Muehlbauer SM, Lima H, Goldman DL, Jacobson LS, Rivera J, Goldberg MF, Palladino MA, Casadevall A, Brojatsch J
Am. J. Pathol., 2010;177(2):735-43. 2010
Effective treatment of a murine model of adult T-cell leukemia using depsipeptide and its combination with unmodified daclizumab directed toward CD25.
Authors: Chen J, Zhang M, Ju W, Waldmann TA
Blood, 2009;113(6):1287-93. 2009
P53-mediated upregulation of DcR1 impairs oxaliplatin/TRAIL-induced synergistic anti-tumour potential in colon cancer cells.
Authors: Toscano F, Fajoui ZE, Gay F, Lalaoui N, Parmentier B, Chayvialle JA, Scoazec JY, Micheau O, Abello J, Saurin JC
Oncogene, 2008;27(30):4161-71. 2008
Differential response of p53 and p21 on HDAC inhibitor-mediated apoptosis in HCT116 colon cancer cells in vitro and in vivo.
Authors: Zopf S, Neureiter D, Bouralexis S, Abt T, Glaser KB, Okamoto K, Ganslmayer M, Hahn EG, Herold C, Ocker M
Int. J. Oncol., 2007;31(6):1391-402. 2007
Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction.
Authors: Karrar A, Broome U, Uzunel M, Qureshi AR, Sumitran-Holgersson S
Gut, 2006;56(2):243-52. 2006
Enhancement of Apo2L/TRAIL-mediated cytotoxicity in esophageal cancer cells by cisplatin.
Authors: Tsai WS, Yeow WS, Chua A, Reddy RM, Nguyen DM, Schrump DS
Mol. Cancer Ther., 2006;5(12):2977-90. 2006
HIV-1 tat protein and cell proliferation and survival: a brief review.
Authors: Gibellini D, Vitone F, Schiavone P, Re MC
New Microbiol., 2005;28(2):95-109. 2005
Ultraviolet light-induced apoptotic death is impaired by the HMG-CoA reductase inhibitor lovastatin.
Authors: Bardeleben R, Kaina B, Fritz G
Biochem. Biophys. Res. Commun., 2003;307(2):401-7. 2003
Caspases as key executors of methyl selenium-induced apoptosis (anoikis) of DU-145 prostate cancer cells.
Authors: Jiang C, Wang Z, Ganther H, Lu J
Cancer Res., 2001;61(7):3062-70. 2001
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