(±)14(15)-EET-d11
货号：
10006410-100ug 基本售价：
7308.0 元 规格：
100 ug
产品信息
概述| 货号 | 10006410-100ug |
| 描述 | (±)14(15)-EET-d11 contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18 ,19, 19 ,20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of (±)14(15)-EET (Item No. 50651) by GC- or LC-MS. (±)14(15)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450.1,2 Dramatic increases in urinary (±)14,15-DiHETrE, a 14(15)-EET metabolite, have been documented by GC/MS in pregnancy-induced hypertension.3 |
| 别名 | (±)14(15)-EpETrE-d11; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Chacos, N.,Falck, J.R.,Wixtrom, C., et al. Novel epoxides formed during the liver cytochrome P-450 oxidation of arachidonic acid. Biochemical and Biophysical Research Communications 104, 916-922 (1982).
2.Oliw, E.H.,Guengerich, F.P., and Oates, J.A. Oxygenation of arachidonic acid by hepatic monooxygenases. Isolation and metabolism of four epoxide intermediates. The Journal of Biological Chemisty 257, 3771-3781 (1982).
3.Catella, F.,Lawson, J.A.,Fitzgerald, D.J., et al. Endogenous biosynthesis of arachidonic acid epoxides in humans: Increased formation in pregnancy-induced hypertension. Proceedings of the National Academy of Sciences of the United States of America 87, 5893-5897 (1990).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% deuterated forms (d1-d11) |
| 计算分子量 | 331.5 |
| 分子式 | C20H21D11O3 |
| 稳定性 | ≥ 1 year |
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