Nitrotyrosine Monoclonal Antibody - Biotinylated
货号：
10006966-100ug 基本售价：
4046.0 元 规格：
100 ug
产品信息
概述| 货号 | 10006966-100ug |
| 描述 | Nitric oxide (NO) is a product of the enzymatic conversion of arginine to citrulline by NO synthase. NO reacts rapidly with superoxide (6.7 x 109 M−1sec−1) to form peroxynitrite. At physiological pH and in the presence of transition metals, peroxynitrite undergoes heterolytic cleavage to form hydroxyl anion and nitronium ion, the latter of which nitrates protein tyrosine residues. Thus, the presence of nitrotyrosine on proteins can be used as a marker for peroxynitrite formation in vivo.1,2 Cayman Chemical’s Nitrotyrosine Monoclonal Antibody - Biotinylated can be used for the species-independent detection of nitrotyrosine using a variety of immunochemical techniques. Biotinylation of the antibody allows for detection using avidin-enzyme or avidin-fluorophore conjugates and provides approximately 2-fold better sensitivity compared to the unbiotinylated antibody (Item No. 189542). |
| 别名 | NT; |
| 来源宿主 | mouse |
| 应用 | ELISA, IHC, IP, and WB |
性能| 供应商 | Cayman |
| 应用文献 |
1.Beckman, J.S.,Chen, J.,Ischiropoulos, H., et al. Oxidative chemistry of peroxynitrite. Methods in Enzymology 233, 229-240 (1994).
2.Beckman, J.S., and Koppenol, W.H. Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and the ugly. American Journal of Physiology 271, C1424-C1437 (1996).
|
| 免疫原 | peroxynitrite-treated KLH |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 稳定性 | ≥ 1 year |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
