Alexa Fluor® 488 Phalloidin
货号：
8878S 基本售价：
5184.0 元 规格：
300assays
产品信息
概述| 货号 | 8878S |
| 反应种属 | All |
| 应用 | IF-F/IF-IC |
| 使用方法 |
IF-IC () |
性能| 供应商 | CST |
| 标记 | Alexa Fluor 488 |
| 背景 | Actin, a ubiquitous eukaryotic protein, is the major component of the cytoskeleton. At least six isoforms are known in mammals. Nonmuscle β- and γ-actin, also known as cytoplasmic actin, are predominantly expressed in nonmuscle cells, controlling cell structure and motility (1). Actin exists mainly as a fibrous polymer, F-actin. In response to cytoskeletal reorganizing signals during processes such as cytokinesis, endocytosis, or stress, cofilin promotes fragmentation and depolymerization of F-actin, resulting in an increase in the monomeric globular form, G-actin (2). Phalloidin is a natually occuring toxic bicyclic peptide found in the deathcap toadstool, Amanita phalloides, that rapidly binds to F-actin with strong affinity (3). |
| 存放说明 | -20C |
参考图片Confocal immunofluorescent analysis of HeLa cells using Alexa Fluor® 488 Phalloidin (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).共聚焦免疫荧光分析HeLa细胞，使用Alexa Fluor® 488 Phalloidin（绿色）。蓝色假色= DRAQ5® #4084（DNA荧光染料）。 |
