产品中心
当前位置:首页>产品中心Anti-Arc1
货号: bs-10793R 基本售价: 1380.0 元 规格: 100ul
- 规格:100ul
- 价格:1380.00元
- 规格:200ul
- 价格:2200.00元
产品信息
- 产品编号
- bs-10793R
- 英文名称
- Arc1
- 中文名称
- ARC1抗体
- 别 名
- Dmel_CG12505; anon-WO0153538.31; anon-WO0153538.40; anon-WO0153538.41; anon-WO0153538.43; anon-WO0153538.45; Arc; CG12505; dArc1; dARC1; Dmel\CG12505; Activity-regulated cytoskeleton associated protein 1; CG12505 gene product from transcript CG12505-RA; CG12505-PA; Arc1-PA.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 昆虫
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Fruit Fly,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 29kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from Fruit Fly Arc1:121-320/254
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Arc, for activity-regulated cytoskeleton-associated protein (also known as Arg3.1), is a plasticity protein first characterized in 1995. Arc is a member of the immediate-early gene (IEG) family, a rapidly activated class of genes functionally defined by their ability to be transcribed in the presence of protein synthesis inhibitors. Arc mRNA is localized to activated synaptic sites in an NMDA receptor-dependent manner, where the newly translated protein is believed to play a critical role in learning and memory-related molecular processes. Arc is widely considered to be an important protein in neurobiology because of its activity regulation, localization, and utility as a marker for plastic changes in the brain. Dysfunctions in the production of Arc protein has been implicated as an important factor in understanding of various neurological conditions including: Amnesia; Alzheimers disease; Autism spectrum disorders; and, Fragile X syndrome. Along with other IEGs such as zif268 and Homer 1a, Arc is also a significant tool for systems neuroscience as illustrated by the development of the cellular compartment analysis of temporal activity by fluorescence in situ hybridization, or catFISH technique (see fluorescent in situ hybridization).
SWISS:
Q7K1U0
Gene ID:
36595
Database links:SwissProt: Q7K1U0 FruitFly
Entrez Gene: 36595 Fruit Fly
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.