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货号： bs-12811R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-12811R
- 英文名称
- ZNF397
- 中文名称
- 锌指蛋白387抗体
- 别 名
- 2810411K16Rik; MGC13250; Zinc finger and SCAN domain containing protein 15; Zinc finger and SCAN domain-containing protein 15; Zinc finger protein 397; Zinc finger protein 47; ZN397_HUMAN; ZNF 397; ZNF 47; ZNF397; ZNF47; ZSCAN 15; ZSCAN15.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 转录调节因子 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 61kDa
- 细胞定位
- 细胞核 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZNF397:131-230/534
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene encodes a protein with a N-terminal SCAN domain, and the longer isoform contains nine C2H2-type zinc finger repeats in the C-terminal domain. The protein localizes to centromeres during interphase and early prophase, and different isoforms can repress or activate transcription in transfection studies. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but their biological validity has not been determined. [provided by RefSeq, Oct 2009]
Function:
Isoform 3 acts as a DNA-dependent transcriptional repressor.
Subcellular Location:
Nucleus and Nucleus. Cytoplasm.
Tissue Specificity:
Expressed strongly in testis, moderately in skeletal muscle, pancreas and prostate, and weakly in heart, placenta, liver, kidney, spleen, thymus and small intestine.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 9 C2H2-type zinc fingers.
Contains 1 SCAN box domain.
SWISS:
Q8NF99
Gene ID:
84307
Database links:Entrez Gene: 506448Cow
Entrez Gene: 100735295 Guinea pig
Entrez Gene: 100052677Horse
Entrez Gene: 84307Human
Entrez Gene: 69256Mouse
Entrez Gene: 100519201Pig
Entrez Gene: 100909408Rat
Omim: 609601Human
SwissProt: Q1LZ87Cow
SwissProt: Q8NF99Human
Unigene: 591061Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.