| 货号 | RDC2118 |
| 别名 | EC 2.7.11.1; Receptor-interacting protein 3; receptor-interacting serine/threonine-protein kinase 3; receptor-interacting serine-threonine kinase 3; RIP3; RIP-3; RIP3receptor interacting protein 3; RIPK3; RIP-like protein kinase 3 | 全称 | Receptor (TNFRSF)-Interacting Serine-Threonine Kinase 3 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 11035 (Human); 56532 (Mouse); 246240 (Rat) |
| 背景 | RIPK3 (), also known as RIP3, is a 518 amino acid (aa), 60 kDa phosphoprotein that contains an N-terminal protein kinase domain and a C-terminal interaction motif with which it binds RIPK1. It converts cell response to TNF-alpha from apoptosis (RIPK1 via Fas) to programmed necrosis (RIPK1/RIPK3) by inducing reactive oxygen species production. Alternately spliced human beta (252 aa) and gamma (231 aa) isoforms diverge after aa 219 and 221, respectively, and are found to antagonize RIP3. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
|