货号 | RDC2022 |
别名 | 9.5S alpha-1-glycoprotein; amyloid P component, serum; APCS; MGC88159; Pentraxin 2; PTX2; PTX2serum amyloid P-component; SAP; SAPpentaxin-related; Serum Amyloid P component | 全称 | Serum Amyloid P Component |
供应商 | R&D Systems |
Entrez Gene IDs | 325 (Human); 20219 (Mouse); 29339 (Rat) |
背景 | Pentraxin or Pentraxin 2 (PTX2), also known as Serum Amyloid P component (SAP), is a secreted serum glycoprotein belonging to the pentraxin superfamily. Pentraxins have a characteristic pentagonal discoid arrangement of five non-covalently bound subunits and bind a variety of molecules in a calcium- dependent lectin-like manner through a pattern-recognition-binding site. PTX2 is a major acute-phase protein and may function as an opsonin for a variety of ligands. PTX2 also associates ubiquitously with all amyloid deposits implicated in diseases including Alzheimers and prion diseases, type 2 diabetes and various systemic amyloidoses. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
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