货号 | RDC2003 |
别名 | EC 2.7.11; EC 2.7.11.1; serine/threonine protein kinase SGK; serine/threonine-protein kinase Sgk1; serum/glucocorticoid regulated kinase 1; serum/glucocorticoid regulated kinase; Serum/glucocorticoid-regulated kinase 1; SGK; SGK1 | 全称 | Serum/Glucocorticoid Regulated Kinase 1 |
供应商 | R&D Systems |
Entrez Gene IDs | 6446 (Human); 20393 (Mouse); 29517 (Rat) |
背景 | SGK1 (Serum- and glucocorticoid-regulated protein kinase 1) is a member of the AGC family of serine/threonine kinases. In addition to serum and glucocorticoids, insulin, IGF-1, osmotic shock, and mineralocorticoids have been demonstrated to activate SGK1. Normally expressed at low levels, SGK1 appears to function as a regulator of epithelial ion transport. Sustained high levels of SGK1 activation have been implicated in hypertension and diabetic nephropathy. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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