货号 | RDC1858 |
别名 | CD64 antigen; CD64; Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc gamma RI; FCG1; Fc-gamma receptor I B2; Fc-gamma RI; Fc-gamma RIA; FcgammaRIa; FCGR1; FcgRI; FCRI; FLJ18345; high affinity Ia, receptor for (CD64); high affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I | 全称 | Fc gamma Receptor I |
供应商 | R&D Systems |
Entrez Gene IDs | 2209 (Human); 2209 (Human); 14129 (Mouse); 295279 (Rat); 295279 (Rat); 102147198 (Cynomolgus Monkey); 102147198 (Cynomolgus Monkey) |
背景 | Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. In humans each group of receptors is encoded by 2 - 3 closely related genes designated A, B, and C. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. Different Fc receptors can function as activators, as inhibitors, or as decoy receptors. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
|