概述货号 | RDC1742 |
别名 | AMH type II receptor; AMHR2; AMHREC 2.7.11.30; AMHRII; C14; MIS RII; MISR2; MISRII; MISRIIMIS type II receptor; MRII; Muellerian hormone type II receptor; Muellerian hormone type-2 receptor; Mullerian hormone receptor, type II; Mullerian inhibiting substance type II receptor |
全称 | Mullerian-Inhibiting Substance Type II Receptor |
性能供应商 | R&D Systems |
Entrez Gene IDs | 269 (Human); 110542 (Mouse); 29530 (Rat) |
背景 | Müllerian inhibiting substance receptor II (MIS RII) is a type II TGF-beta superfamily receptor that forms a heteromeric complex with various type I receptors to mediate MIS signaling. Mature MIS RII has a cysteine-rich, glycosylated, extracellular domain, and a cytoplasmic region containing a serine/threonine kinase domain. Rat MIS RII shares 95% and 82% aa sequence identity with its mouse and human orthologs, respectively. Embryonically, it is expressed in mesenchymal cells surrounding the Müllerian ducts. Postnatally, it is expressed in uterine tissues and Leydig cells, showing coexpression with MIS in the testicular Sertoli and ovarian granulosa cells. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | - ICC / IHC Images: MIS RII
- TGF-beta Family
- TGF-beta Superfamily
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