概述| 货号 | RDC1722 |
| 别名 | CD158 antigen-like family member A; CD158a antigen; CD158a; CD158Ankat1; cl-42; killer cell immunoglobulin-like receptor 2DL1; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1; killer Ig receptor; killer inhibitory receptor 2-2-1; KIR221; KIR2DL1; MHC class I NK cell receptor; Natural killer-associated transcript 1; NKAT; NKAT-1; NKAT1KIR-K64; p58 killer cell inhibitory receptor KIR-K64; p58 natural killer cell receptor clones CL-42/47.11; p58 NK cell inhibitory receptor NKR-K6,47.11; p58 NK receptor CL-42/47.11; p58.1 MHC class-I-specific NK receptor; p58.1 |
全称 | Killer Cell Immunoglobulin-like Receptor, Two Domain Long Cytoplasmic Tail, 1 |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3802 (Human) |
| 背景 | The KIR family is composed of at least 15 members expressed by natural killer (NK) cells and a subset of T cells in primates only. KIR proteins are named based on the number of extracellular Ig-like domains (KIR2D or KIR3D) and for whether the cytoplasmic domain is long (L), or short (S). Inhibitory KIR proteins possess long cytoplasmic tails with ITIM (inhibitory) domains, and several of these molecules bind HLA Class I molecules or target cells. Activating KIR proteins have short tails; their targets are less well-known. KIR2DL4 (CD158d) is unique in that it shows both inhibitory and activating characteristics. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Human CD Marker Products
- ITIM/ITAM Immunoreceptors and Related Molecules
- Killer Immunoglobulin-like Receptors (KIRs)
- Natural Killer T (NKT) Cells
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