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货号: bs-21062R 基本售价: 1380.0 元 规格: 100ul
- 规格:100ul
- 价格:1380.00元
- 规格:200ul
- 价格:2200.00元
产品信息
- 产品编号
- bs-21062R
- 英文名称
- PPIP5K2/HISPPD1
- 中文名称
- 组氨酸酸性磷酸酶结构域蛋白1抗体
- 别 名
- Diphosphoinositol pentakisphosphate kinase 2; HISPPD1; Histidine acid phosphatase domain containing 1; Histidine acid phosphatase domain containing protein 1; Histidine acid phosphatase domain-containing protein 1; hsVIP2; Inositol heptaphosphate kinase 2; Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2; InsP6 and PP IP5 kinase 2; InsP6 and PP-IP5 kinase 2; IP7K2; PP IP5 kinase 2; Ppip5k2; VIP1 homolog 2; VIP2; VIP2_HUMAN.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 肿瘤 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 138kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PPIP5K2/HISPPD1:651-750/1243
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively (Fridy et al., 2007 [PubMed 17690096]).[supplied by OMIM, Mar 2008]
Function:
Bifunctional inositol kinase that catalyzes the formation of diphosphoinositol pentakisphosphate (InsP7 or PP-InsP5) and bi-diphosphoinositol tetrakisphosphate (InsP8 or PP2-InsP4). Converts inositolitol hexakisphosphate (InsP6) to InsP7. Also able to convert InsP7 to InsP8. Probably specifically mediates the formation of 4PP-InsP5 and 6PP-InsP5 InsP7 isomers but not of 5PP-IP5 InsP7 isomer.
Subcellular Location:
Cytoplasm >cytosol.
Tissue Specificity:
Belongs to the histidine acid phosphatase family. VIP1 subfamily.
Similarity:
Belongs to the histidine acid phosphatase family. VIP1 subfamily.
SWISS:
O43314
Gene ID:
23262
Database links:Entrez Gene: 101091503Cat
Entrez Gene: 780855Cow
Entrez Gene: 488883Dog
Entrez Gene: 100712709 Guinea pig
Entrez Gene: 100064726Horse
Entrez Gene: 23262Human
Entrez Gene: 227399Mouse
Entrez Gene: 501194Rat
Omim: 611648Human
SwissProt: O43314Human
SwissProt: Q6ZQB6Mouse
Unigene: 212046Human
Unigene: 220817Mouse
Unigene: 417682Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.