概述| 货号 | RDC1883 |
| 别名 | CD305 antigen; CD305; CD305leukocyte-associated Ig-like receptor 1; hLAIR1; LAIR1; LAIR-1; leukocyte-associated immunoglobulin-like receptor 1 |
全称 | Leukocyte-associated Ig-like Receptor 1 |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3903 (Human) |
| 背景 | LAIR proteins are related proteins that each contain one Ig-like domain and thus belong to the Ig superfamily. LAIR1 is a type I transmembrane protein with two cytoplasmic ITIM domains that functions as an inhibitory receptor on NK cells, T cells, B cells, monocytes, dendritic cells and most thymocytes. LAIR2 is a secreted protein with 83% amino acid identity to LAIR1 extracellular domain, but lacks the transmembrane and cytoplasmic domains. The function of LAIR2 is not known. Both LAIR1 and LAIR2 have alternately spliced isoforms. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - B Cell Activation
- Co-stimulatory and Co-inhibitory Molecules
- Dendritic Cell ITIM/ITAM Immunoreceptors
- ITIM/ITAM Immunoreceptors and Related Molecules
- Monocyte Markers
- T Cell Migration/Adhesion
- Thymocytes
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