概述货号 | RDC1708 |
别名 | 2F1; CLEC15A; CLEC15AMAFA-LIKE; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; MAFA; MAFAL; MAFA-L; MAFA-like receptor; MAFAMAFA-2F1; mast cell function-associated antigen (ITIM-containing); Mast cell function-associated antigen; MGC13600 |
全称 | Killer Cell Lectin-like Receptor Subfamily G Member 1 | 反应种属 | Human |
性能供应商 | R&D Systems |
Entrez Gene IDs | 10219 (Human); 50928 (Mouse); 58975 (Rat) |
背景 | KLRG1 (killer cell lectin-like receptor G1), also called MAFA (mast cell function associated), is a 30-38 kDa type II transmembrane inhibitory glycoprotein of the C-type lectin family, designated CLEC15A. KLRG1 binds E-, N- and R-cadherins and functions as an MHC-independent means of identifying non-self pathogens and epithelial tumor cells with low E-cadherin expression. It is expressed as a monomer or disulfide-linked homodimer on NK and T cell subsets such as tumor-infiltrating lymphocytes. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | - Group 2 ILCs
- ITIM/ITAM Immunoreceptors and Related Molecules
|