概述| 货号 | RDC1485 |
| 别名 | CD371; CLEC12A; CLL1; CLL-1; C-type lectin domain family 12, member A; DCAL-2; MICL |
全称 | Myeloid Inhibitory C-type Lectin-like Receptor | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 160364 (Human); 232413 (Mouse) |
| 背景 | MICL is a member of the group V subfamily of the C-type lectin-like family of molecules. It is found on the cell surface, contains an ITIM (immunoreceptor tyrosine-based inhibitory motif) in its cytoplasmic domain, and is N-glycosylated. Expression of MICL is restricted to granulocytes and monocytes, and it may function as a negative regulator of these cell types. At least three isoforms of MICL are generated by alternative splicing, including one that lacks the transmembrane domain. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Cancer Stem Cell Markers
- C-type Lectin Family
- C-type Lectin Receptors
- Interactive Pathway: Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways
- ITIM/ITAM Immunoreceptors and Related Molecules
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