概述| 货号 | RDC0308 |
| 别名 | MAS-related GPR, member X2; mas-related G-protein coupled receptor member X2; MRGPRX2; MRGX2G protein-coupled receptor MRGX2 |
全称 | Mas-related G Protein-coupled Receptor Member X2 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 117194 (Human); 243978 (Mouse) |
| 背景 | MRGX2 (MAS-related GPR, member X2) is G-protein coupled 7-transmembrane protein that is selectively expressed in small-diameter sensory neurons of dorsal root ganglia. Human MRGX shares 41-52% amino acid identity with three other primate MRGX proteins, but has no ortholog in rodents. Binding of ligands such as cortistatin, proadrenaomedullin peptides (PAMP-12 and -20) and basic peptides (substance P, neuropeptide Y) to MRGX2 can activate Gq or Gi regulated pathways. MRGX2 is thought to influence nociception and promote adrenal gland catecholamine secretion and IgE-independent mast cell degranulation. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Neurotransmitter G Protein-Coupled Receptors
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