Human Dectin-1/CLEC7A (NP 072092) VersaClone cDNA (10 UG)
货号：
RDC1474 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC1474 |
| 别名 | Beta-glucan receptor; BGR; CD369; CLEC7A; CLECSF12; CLECSF12DC-associated C-type lectin 1; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; dectin-1; DECTIN1CANDF4; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; hDectin-1; lectin-like receptor 1 |
| 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 64581 (Human); 56644 (Mouse) |
| 背景 | Dectin-1, also known as CLEC7A, is a transmembrane C-type lectin that participates in the innate immune response to fungal pathogens. It is expressed on the surface of monocytes, macrophages, myeloid DC, neutrophils, eosinophils, B cells, and CD4+ T cells. Dectin-1 selectively binds beta-glucan polymers, a major component of yeast and mycobacterial cell walls. Dectin-1 mediates the phagocytosis of zymosan particles and intact yeast. Dectin-1 colocalizes with TLR2 in the presence of zymosan, and the two receptors cooperate in ligand recognition and the propagation of proinflammatory signaling. Dectin-1 also interacts with tetraspanin CD37 which increases its stability on the cell membrane and inhibits ligand-induced signaling. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Co-stimulatory and Co-inhibitory Molecules
- C-type Lectin Family
- C-type Lectin Receptors
- Dendritic Cell Co-stimulatory Molecules
- Dendritic Cell ITIM/ITAM Immunoreceptors
- Dendritic Cell Pathogen Recognition/Uptake
- gamma delta T Cells
- ICC / IHC Images: Dectin-1/CLEC7A
- Interactive Pathway: Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways
- ITIM/ITAM Immunoreceptors and Related Molecules
- Macrophage Activation Markers
- Mouse Tissue-Resident Macrophage Markers
- T Cell Antigen Recognition
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