概述| 货号 | RDC1543 |
| 别名 | CD113 antigen; CD113; CDw113FLJ90624; DKFZp566B0846; nectin 3; nectin-3; poliovirus receptor-related 3; poliovirus receptor-related protein 3; PPR3; PRR3CD113; PVRL3; PVRR3 |
全称 | Poliovirus Receptor Related 3 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 25945 (Human) |
| 背景 | Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs). Homology has led to their designation as poliovirus receptor-related (PRR) proteins, but nectins do not bind poliovirus. The extracellular domains of the nectin family form cis-homodimers (same cell), followed by homophilic or heterophilic trans-dimers (across cells) that organize intercellular junctions. Nectin-1, also known as CD111, PRR1 and herpes virus entry mediator C (HVEC) has a secreted splice variant. Nectin-1, Nectin-2 (CD112, PRR2, HVEB) and Nectin-3 (PRR3) are concentrated in adherens junctions and exist on neurons, endothelial cells, epithelial cells and fibroblasts. Nectin-4 is mainly expressed in the placenta; a soluble form is generated via the action of TACE/ADAM17. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Cell to Cell Adhesion Disassembly During EMT
- Co-stimulatory and Co-inhibitory Molecules
- Epithelial Cell Markers and Intracellular Molecules
- Epithelial Cell Polarity
- Human CD Marker Products
- ICC / IHC Images: Nectin-3
- Immunoglobulin Superfamily CAMs
- Infectious Diseases
- Nectin and Nectin-like Binding Receptors and Ligands
- Nectins
- Surface Ectodermal Cells
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