概述| 货号 | RDC1628 |
| 别名 | CLAXLLT-1; CLEC2D; C-type lectin domain family 2 member D; C-type lectin domain family 2, member D; C-type lectin related f; Lectin-like NK cell receptor; Lectin-like transcript 1; LLT1; LLT1Osteoclast inhibitory lectin; OCILmember D |
全称 | Osteoclast Inhibitory Lectin | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 29121 (Human); 93694 (Mouse) |
| 背景 | OCIL/CLEC2D, also known as lectin-like transcript-1 (LLT-1), is a type II transmembrane protein belonging to the natural killer cell receptor group of the C-type lectin superfamily. It is found on hematopoietic cells, osteoblasts, and chondrocytes. Human OCIL preferentially binds high molecular weight sulfated glycosaminoglycans and is a ligand for the single human NKR-P1A receptor (CD161). Human OCIL blocks osteoclast differentiation. Engagement of OCIL with CD161 on NK cells also inhibits NK cell-mediated cytotoxicity and IFN-gamma secretion. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | |
