Human CD1c/BDCA-1 (NP 001756) VersaClone cDNA (10 UG)
货号：
RDC1272 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC1272 |
| 别名 | BDCA1; BDCA-1; c polypeptide; CD1; CD1A; CD1c antigen; CD1c molecule; CD1c; cortical thymocyte antigen CD1C; differentiation antigen CD1-alpha-3; R7; T-cell surface glycoprotein CD1c |
| 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 911 (Human) |
| 背景 | Cluster of Differentiation Antigen 1c/Blood Dendritic Cell Antigen 1 (CD1c/BDCA-1) is a transmembrane glycoprotein in the CD1 family of MHC-like molecules. It is expressed by humans but not by mice or rats. Human CD1c/BDCA-1 is a 316 amino acid protein with a predicted molecular weight of 43 kDa. It binds to lipid and glycolipid antigens and presents them to T cells. CD1c/BDCA-1 is expressed by dendritic cells and B cells, where it traffics between endosomes and the plasma membrane. Heterodimerization with beta-2-Microglobulin is required for CD1c membrane trafficking. CD1c is thought to present a wide variety of lipids to T cells and has been shown to mediate T cell activation in response to Mycobacterium tuberculosis. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - B Cell Markers
- Conventional/Classical Dendritic Cells
- Inflammatory/Monocyte-derived Dendritic Cells
- Langerhans and Dermal Dendritic Cells
- T Cell Antigen Recognition
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